| Renal Fellows, Practicing Physicians, Immunologists, and Transplant Surgeons Table of Contents Chapter 1. Immunobiology and Evaluation Techniques………………………………………………………………… 1 1.1 Transplant Immunobiology 1 Shruti Tapiawala, Suchita Jogale 1.2 Immunologic Evaluation of Kidney Transplant Candidates 10 Ajay Kumar Baranwal, Uma Kanga 1.3 Donor-specific Antibodies in Kidney Transplantation 26 Rahul Grover, Narayan Prasad 1.4 Role of non-HLA Antigen in Kidney Transplantation 34 Jasmine Sethi, Vivek Kumar 1.5 Tolerance and Accommodation in Renal Transplantation 38 Aruna V Vanikar, Pankaj R Shah Chapter 2. Evaluation of Living Kidney Donors…………………………………………………………………….49 Ajit S Narula, Mastakim A Mazumder Chapter 3. Evaluation of Kidney Transplant Recipients……………………………………………………………….56 Edwin Fernando, Sukanya Govindan Chapter 4. Surgical Techniques of Kidney Transplantation………………………………………………………..61 Sandeep Guleria Chapter 5. Surgical and Vascular Complications After Kidney Transplantation…………………………………………………………72 Aneesh Srivastava, Akshay Kriplani Chapter 6. Perioperative Care of Kidney Transplant Recipient…………………………………………………………………83 Ratan Jha, Rakesh Kumar Ambati, Aman Jha Chapter 7. Kidney Transplantation in Abnormal Urinary Bladder……………………………………………………………………89 PP Varma, Prateek Kumar Chapter 8. Evaluation of Acute Allograft Dysfunction……………………………………………………………..95 Joyita Bharati, Harbir S Kohli Chapter 9. Immunosuppressive Drugs……………………………………………………………………100 9.1 Induction Therapy in Kidney Transplantation 100 Arunkumar S, D Bhaumik 9.2 Steroid 106 Kapil N Sejpal, PS Priyamvada 9.3 Calcineurin Inhibitors 114 Abhijit Taraphder, Padmini Sirkanungo, Govardhan Gupta 9.4 Mycophenolate Mofetil 120 Kristin George, Soumita Bagchi 9.5 mTOR Inhibitors 126 Pallavi Prasad, Dinesh Khullar 9.6 Azathioprine 131 Umapati Hegde 9.7 Belatacept 136 Anshul Bhalla, Divyanshu Malhotra Chapter 10. Allograft Rejection……………………………………………………………….142 10.1 Acute Allograft Rejection 142 Anna Gupta, Mehakinder Singh, Raja Ramachandran 10.2 Chronic Allograft Rejection 147 Praveen Kumar Etta, Arpita Ray Chaudhury Chapter 11. Histopathology of Kidney Transplantation………………………………………………………160 Swarnalata Gowrishankar, Pallav Gupta Chapter 12. Infections in Kidney Transplantation………………………………………………………176 12.1 Overview of Infections in Kidney Transplantation 176 Vaibhav Tiwari, AK Bhalla, Ashwani Gupta 12.2 Viral Infections 181 12.2.1 Cytomegalovirus 181 K Sampathkumar 12.2.2 BK Virus Nephropathy 186 Raj Kumar Sharma, Sonia Mehrotra 12.2.3 Hepatitis C Virus 195 Ruju Gala, Narayan Prasad 12.2.4 Hepatitis B Virus 202 Kalpana Shailesh Mehta, Atim Pajai 12.2.5 Human Immunodeficiency Virus 207 Anwitha Varmudy, Sree Bhushan Raju 12.2.6 Other Viral Infections 212 Mayuri Trivedi, Krishna Kumar Agrawaal 12.3 Fungal Infections 219 N Gopalakrishnan, Tanuj M Lamech, Venkatesh Arumugam 12.4 Parasitic Infections 226 Dharmendra Bhadauria, B Karthikeyan 12.5 Pneumocystis jirovecii 238 Tukaram Jamale, Nikhil Saxena 12.6 Urinary Tract Infection 244 Krishan Lal Gupta, Joyita Bharati 12.7 Tuberculosis 248 Arunkumar S, Sanjay K Agarwal 12.8 Nocardiosis 255 Shiv Chadha, Vaibhav Tiwari, Manish Malik, Pallav Gupta Chapter 13. Noninfectious Complications…………………………………………………………260 13.1 Cardiovascular Disease in Kidney Transplant Recipients 260 Jony Agarwal, Shahzad Alam, Amit Gupta 13.2 Hepatic Dysfunction in Kidney Transplant Recipients 269 Ashish Kumar 13.3 Neurological Disorders in Kidney Transplant Recipients 275 Priti Meena, Arvind Canchi 13.4 Hypertension in Kidney Transplant Recipients 281 Santosh Varughese, Jeethu Joseph Eapen 13.5 Diabetes Mellitus After Kidney Transplantation 289 Niwrutti Hase, Aniket Hase 13.6 Mineral Bone Disease in Kidney Transplant Recipients 301 Vinant Bhargava, Anurag Gupta, Shyam Bansal 13.7 Malignancy in Kidney Transplant Recipients 308 Arunkumar S, Sandeep Mahajan 13.8 Hematological Disorders in Kidney Transplant Recipients 314 Rajendra Prasad Mathur, Chandani Bhagat Chapter 14. Recurrent and de novo Glomerulonephritis After Kidney Transplantation…………………………………………….323 Sabina Yusuf, Suceena Alexander Chapter 15. Kidney Transplantation in Primary Hyperoxaluria…………………………………………………………334 Susan Uthup Chapter 16. Chronic Allograft Injury……………………………………………………………………343 Arpita Ray Chaudhury, Saugat Dasgupta Chapter 17. Management of Patients with Failed Renal Allograft………………………………………………………………..350 Jasmine Sethi, Vinay Sakhuja Chapter 18. Radiological Imaging and Biopsy Technique in Kidney Allograft………………………………………………………355 Ujjwal Gorsi, Prabhjyot Singh Chowhan Chapter 19. HLA Incompatible Kidney Transplantation………………………………………………………370 Alan Almeida, Ayan Dey Chapter 20. ABO-incompatible Kidney Transplantation………………………………………………………378 Pranaw K Jha, Vijay Kher Chapter 21. Kidney Paired Donation in India: Status, Challenges, and Recommendations…………………………….387 Vivek Kute, Priti Meena, Manisha Sahay, Sanshriti Chauhan, Hari Shankar Meshram Chapter 22. Deceased Donation………………………………………………………………..393 22.1 Deceased Donor Care 393 Indira Menon, Sunil Shroff, Chacko Korula Jacob 22.2 Allocation Criteria 401 Jayasurya R, Sreejith Parameswaran 22.3 How to Set Up a Deceased Donor Program 406 Noble Gracious, Georgi Abraham Chapter 23. Kidney Transplantation in Children…………………………………………………………………415 Arpana Iyengar, Arvind Bagga Chapter 24. Reproductive Health in Kidney Transplantation …………………………………………………………………………….425 Urmila Anandh, Swarnalatha Guditi, Divya Bajpai Chapter 25. Vaccination in Kidney Transplant Recipients………………………………………………………………432 Gokulnath, Prashant C Dheerendra Chapter 26. Combined Liver Kidney Transplantation………………………………………………………438 Venu Madhav Thumma, Sukanya Bhrugumalla Chapter 27. Combined Kidney Pancreas Transplantation………………………………………………………443 B Ramesh Kumar, Manisha Sahay Chapter 28. Psychological Issues in Kidney Transplant Recipients………………………………………………………………450 Surendra K Mattoo, Akhilesh Sharma, Ajaypal Singh Chapter 29. Transplantation of Human Organs and Tissues Act: Simplified………………………………………………………..459 Manisha Sahay Index……………………………………………………………………..467 | Editors: Vinant Bhargava | DNB (Medicine) DNB (Nephrology) MNAMS FASN FRCP (Edinburgh) FACP MBA (HCM) | | | Manisha Sahay | MD (Pediatrics) DNB (Pediatrics) DM (Nephrology) DNB (Nephrology) FRCP | | | Priti Meena | MD (Medicine) DrNB (Nephrology) FASN | | | Vinay Sakhuja | MD (Medicine) DM (Nephrology) MNAMS (Nephrology) | | | Amit Gupta | MD (Medicine) DNB (Nephrology) FRCP (London) |
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