Descripción
Personalized Cancer Therapy
Advances in Precision Medicine for Targeted Cancer Treatment
- Book
- © 2026
Editors:
- Mrinal K. Ghosh,
- Malini Basu
- Covers precision medicine from fundamental principles to cutting-edge technologies
- Provides cancer-specific molecular profiling and therapeutic strategies by integrating genomics, epigenomics, etc.,
- Explores novel trial designs, diagnostic advances, and therapeutic applications directly translatable
About this book
This book offers a definitive and comprehensive exploration of precision medicine, capturing both its foundational principles and cutting-edge innovations. Organized into six sections, it guides readers from the basics of individualized healthcare to the advanced application of genomics, epigenomics, pharmacogenomics, and artificial intelligence in cancer treatment. Through detailed cancer-specific chapters—covering gliomas, head & neck cancers, breast, lung, prostate, colon, pancreatic, and other malignancies—the book delivers in-depth insights into molecular profiling, diagnosis, and personalized therapy strategies. Beyond scientific advances, it critically addresses the ethical, clinical, and social dimensions of precision medicine, preparing clinicians, researchers, and policymakers to navigate challenges and harness the future opportunities in this transformative field. By blending scientific rigor with forward-looking perspectives, this volume positions itself as an authoritative reference for oncology researchers, clinicians, bioinformaticians, pharmaceutical scientists, and graduate students seeking to understand and contribute to the future of personalized healthcare.
Table of contents (24 chapters)
- Front Matter
- Pages i-xxvii
- Introduction to Precision Medicine
- Genomics, Epigenomics and Pharmacogenomics
- Front Matter
- Pages 47-47
- Genomics and Key Alterations
- A. Esmaeilzadeh, F. Ebrahimi, M. H. Makoui, K. Hadiloo, S. Taremi, K. Esmaeilzadeh et al.
Pages 49-65
- Cancer Epigenomics in Precision Medicine
- A. Esmaeilzadeh, M. Hassanzadeh Makoui, F. Ebrahimi, S. Taremi, P. M. Yeganeh, F. Afshari et al.
Pages 67-92
- Pharmacogenomics in Personalised Treatment
- Sayani Ghosh, Sunny Kumar, Malini Basu
Pages 93-109
- Precision Cancer Medicine in Clinical Trial Design
- Arijit Bhowmik, Souvik Das. Sandip Ghosh, Biswarup Basu
Pages 111-134
- Clinical Implementation and Outcomes of Personalized Cancer Therapy
- Kirat Kumar Ganguly
Pages 135-152
- Cancer Specific Molecular Profiling, Diagnosis and Treatment
- Front Matter
- Pages 153-153
- Advanced Personalized Treatment Strategies for Glioblastoma
- Sunny Kumar, Mrinal K. Ghosh
Pages 155-174
- Personalized Treatment Options in Head and Neck Cancer
- Sourav Sanyal, Arundhaty Pal, Sumita Bandyopadhyay Sengupta, Tapas Kumar Sengupta
Pages 175-193
- Breast Cancer: Targeted Therapy and Neoantigen Vaccine
- Shaonlee Ghosh, Gourab Das, Abhijit De
Pages 195-210
- Personalized Therapy in Non-Small-Cell Lung Cancer
- Chandreyee Datta, Arpita Mukherjee, Sourav Paul, Ashish Bhattacharjee
Pages 211-233
- Personalized Medicines and Prospects in Prostate Cancer
- Yogesh Vaishnav, Shikha Agarwal, Joohee Pradhan, Mayank Garhewal, Ashish Baldi
Pages 235-255
- Breakthroughs in Personalized Treatment of Colorectal Cancer
- Rajni Shaw, Sibani Sarkar, Mrinal K. Ghosh
Pages 257-276
- Innovative Approaches in Pancreatic Cancer Treatment
- Arisha Arora, Basab Ghosh, Pijush Kanti Khanra, Sailayee Choudhury, Siddhartha Sankar Ghosh
Pages 277-298
- Advancements in Hematopoietic Cancer Treatment
- Subhajit Karmakar, Mouli Chatterjee, Malini Basu
Pages 299-316
- Nanotherapeutics in Personalized Medicine
- Front Matter
- Pages 317-317
Nanotherapeutics in Personalized Medicine
Nanotherapeutics in Cancer Therapy: Targeted Drug-Delivery and Real-Time Monitoring
Biomarker Identification Using Nanoparticles
Challenges, Limitations and Social Considerations
Front Matter
Personalized Cancer Therapy: Technical and Clinical Challenges
Successfully Financing Personalized Cancer Drug Therapy for All: A Social Policy Perspective
Role of Health Workers in Personalized Medicine
Novel Innovations and Future Perspectives
Front Matter
Emerging Technologies and Approaches
Applications of Bioinformatics and Computational Biology
Artificial Intelligence (AI) and Machine Learning (ML) in Personalized Medicine
Potential Breakthroughs and Future Research Directions
Editors and Affiliations
Department of Cancer Biology and Inflammatory Disorder Division, CSIR-Indian Institute of Chemical Biology (IICB), Kolkata, India
Mrinal K. Ghosh
Department of Microbiology, Dhruba Chand Halder (DCH) College, University of Calcutta, Kolkata, India
Malini Basu
About the editors
Dr. Mrinal K Ghosh is a Chief Scientist, In-Charge of CSIR-IICB (TRUE), Salt Lake Campus and Head (2019-2025) of the Cancer Biology and Inflammatory Disorder Division at CSIR-IICB, Kolkata, India; Chairman of management council at CSIR-IICB (TRUE) and a Professor at the Academy of Scientific and Innovative Research (AcSIR), India. He completed his Ph.D. from the University of Calcutta and Post-doctoral research (1997 – 2005) from Lerner Research Institute, Cleveland Clinic Foundation, OHIO, USA. Dr. Ghosh’s research interests include signal transduction in cancer focusing on the regulation of various oncogenes and tumor suppressor proteins, and developing nanotechnology-based targeted drug delivery systems to the targets (identified molecular vulnerabilities) in brain, breast, and colon cancers. He has published 81 papers in peer-reviewed international journals, Edited one book, and authored several book chapters. Dr. Ghosh delivered numerous lectures, and is a reviewer of various national and international journals and research project proposals of World Cancer Research, Ireland Research Board, ICMR, DBT, DST. Dr. Ghosh is a lifetime member of the Indian Society of Translational Research (ISTR), the Chemical Biology Society (CBS), the Indian Association of Cancer Research (IACR), the Society of Biological Chemistry (SBC), and the Indian Science Congress Association (ISCA), India.
Dr. Malini Basu is an Assistant Professor and Head, Department of Microbiology, Dhruba Chand Halder College, University of Calcutta, Kolkata, India. She completed her Ph.D. from the University of Calcutta and Post-doctoral research from Case Western Reserve University (CWRU), USA in collaboration with Rainbow Babies and Children Hospital, Ohio, USA. Dr. Basu’s research interests include heavy metals, microbial bioremediation and bioindicators, unique virulence, pathogenicity, and host-immune response of Helicobacter pylori in gastric cancer. She has published several papers in peer-reviewed national and international journals and some book chapters. Dr. Basu is a lifetime member of the Microbiologists Society India (MBSI), the Association of Microbiologists of India (AMI), ISCA and ISNA. She is also the state vice-president of the Microbiologists Society of India.
Bibliographic Information
- Book Title Personalized Cancer Therapy
- Book Subtitle Advances in Precision Medicine for Targeted Cancer Treatment
- Hardcover ISBN 978-981-95-6844-4Published: 24 April 2026
- Softcover ISBN 978-981-95-6847-5Due: 08 May 2027
- Edition Number 1
- Number of Pages XXVII, 479
- Number of Illustrations 4 b/w illustrations, 53 illustrations in colour
- Topics Cancer Research, Genetics and Genomics, Oncology, Bioinformatics, Medicine/Public Health, general
Keywords
- Cancer-specific Perspective of Personalized Medicine
- Identification and Validation of Cancer Biomarkers
- Personalized Drug Selection based on Pharmacogenomic Profiles
- Bioinformatics-based Approach for Precision Medicine
- Clinical Implementation and Patient Outcomes
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