Descripción
Percutaneous Interventions for Structural Heart Disease
An Illustrated Guide
- Book
- © 2026
- Latest edition
Editors:
- Bernhard Reimers,
- Azeem Latib,
- Antonio Mangieri,
- Issam Moussa,
- Damiano Regazzoli,
- Andrea Pacchioni
- Updated review of the current panorama of interventional procedures
- Step-by-step procedures description, paralleled by informative illustrations
- Case-based analysis of the most common structural pathologies and their complications
About this book
The second edition of this book offers an overview of the percutaneous techniques and technologies most frequently employed in structural heart intervention, focusing on patient selection, preoperative evaluation, choice of available devices and outcome optimization. Interventional procedures for aortic stenosis, mitral regurgitation, left atrial appendage closure, patent foramen ovale closure, and closure of interatrial and interventricular defects are presented in a step by step fashion, and paralleled by informative illustrations. This new edition of Percutaneous Intervention for Structural Heart Disease aims to adjourn the reader on structural heart intervention not only as per current standard practice, but also on uprising topics such as percutaneous treatment of tricuspid regurgitation and paravalvular leak closure. Advances made in recent years, including introduction and optimization of transcatheter aortic valve implantation in patients with severe aortic stenosis independently from estimated surgical risk and implementation of percutaneous edge-to-edge mitral valve repair for functional mitral regurgitation, will be taken into account. The authors are all acknowledged experts with extensive experience in catheterization laboratories and surgical operating rooms.
Table of contents (42 chapters)
- Front Matter
- Pages i-xv
- Aortic Valve Intervention
- Front Matter
- Pages 1-1
- Severe Aortic Stenosis Treatment: Percutaneous Options, Patient Selection, and Preoperative Evaluation
- Renato Razzolini, Elisa Covolo, Chiara Fraccaro
Pages 3-11
- Echocardiographic and Magnetic Resonance Imaging Evaluation
- Martina Maria Ruffo, Federica B. B. Testerini, Dario Donia, Stefano Frittella, Francesco Paolo Sinagra, Silvana Di Maio
Pages 13-28
- Computed Tomography: Device and Strategy Planning
- Michele Rinaldi, Andrea Arneri
Pages 29-63
- TAVR: Commercially Available Devices
- Riccardo Gorla, Enrico Criscione, Mattia Squillace, Francesco Bedogni
Pages 65-74
- Transfemoral Access Assessment for Structural Heart Interventions
- Valentina Bernardini, Matteo Nardin, Gianluca Mincione, Davide Cao
Pages 75-92
- Alternative Access Transcatheter Aortic Valve Implantation (TAVI)
- Ozan Demir, Neil Ruparelia
Pages 93-102
- How to Manage Hostile Anatomies: Large and Small Annuli, Severely Calcific Anatomy, and Severe Left Ventricular Outflow Tract Hypertrophy
- Francesco Gallo, Alessandra Laricchia, Carolina Montonati, Mariano Pellicano, Alfonso Ielasi, Giorgos Tzanis et al.
Pages 103-118
- Transcatheter Aortic Valve Implantation in Bicuspid Aortic Valves
- Omar A. Oliva, Chiara De Biase, Didier Tchétché
Pages 119-124
- How to Avoid and Manage Acquired Conduction Disorders After TAVI
- Antonio Mangieri, Laura Novelli, Gulrays Jamie
Pages 125-132
- Valve-in-Valve Procedures as a First-Line Strategy for Degenerated Aortic Bioprosthesis
- Marco Barbanti, Orazio Strazzieri, Silvia Motta, Corrado Tamburino
Pages 133-157
- Cerebral Embolic Protection
- Carlo Giacari, Matteo Biroli, Marco Gennari, Federico De Marco
Pages 159-173
- TAVR in Patients at High Risk of Coronary Obstruction: Procedural Considerations and Management
- Arif A. Khokhar, Alessandro Beneduce, Francesco Giannini, Iqbal Malik
Pages 175-190
- Future TAVI Challenges: Asymptomatic Aortic Stenosis, Moderate Aortic Stenosis with Heart Failure and TAVI-in-TAVI Procedures
- Arif A. Khokhar, Carla Lucarelli, Saud A. Khawaja, Ghada W. Mikhail
Pages 191-212
- Future Challenges: Transcatheter Aortic Valve Implantation for Pure Aortic Regurgitation
- Pier Pasquale Leone, Abdullah Aftab, Damiano Regazzoli, Bernhard Reimers
Pages 213-221
- Difficult Cases and Complications from Catheterization Laboratory: Preventing Coronary Artery Obstruction with a Double Chimney During ViV-TAVI
- Edoardo Pancaldi, Marianna Adamo
Pages 223-229
- Difficult Cases and Complications from the Catheterization Laboratory: Case 1: Acute Massive Aortic Regurgitation Secondary to Prosthetic Cusp Eversion Successfully Treated with Valve-in-Valve TAVR with Double Chimney Stenting
- Matteo Maurina, Paolo Pagnotta, Antonio Mangieri, Bernhard Reimers, Damiano Regazzoli
Pages 231-240
- Valve-in-Valve Transcatheter Aortic Valve Implantation (VIV-TAVI) with Bioprosthetic Aortic Scallop Intentional Laceration to Prevent Iatrogenic Coronary Obstruction (BASILICA) and Bioprosthetic Valve Fracture (BVF)
- Joachim Schofer, Christina Brinkmann
Pages 241-245
- Self-Expanding Transcatheter Heart Valve Infolding: Different Clinical Presentations and Management
- Tommaso De Ferrari, Marco B. Ancona, Luca A. Ferri, Filippo Russo, Barbara Bellini, Ciro Vella et al.
Pages 247-251
Mitral Valve Intervention
Front Matter
Mitral Regurgitation Treatment: Patient Selection and Procedural Planning
Multimodality Imaging in Transcatheter Mitral Valve Interventions
Coaptation Augmentation Devices
Direct and Indirect Annuloplasty for Functional Mitral Regurgitation
Percutaneous Interventions for Mitral Annular Calcification
Transcatheter Mitral Valve Replacement
Difficult Cases and Complications from Catheterization Laboratory—Case 3: Structural Device Failure After MitraClip Implantation Due to Iatrogenic Chordal Rupture
Tricuspid Valve Interventions
Front Matter
Tricuspid Regurgitation: From Patient Selection to Procedural Guiding with Echocardiography
Multimodality Imaging in Transcatheter Tricuspid Valve Interventions
Percutaneous Tricuspid Valve Repair
Transcatheter Tricuspid Valve Replacement
Caval Valve Implantation
Valve-in-Valve and Valve-in-Ring on Tricuspid Valve
Transcatheter Edge-to-Edge Repair in a Patient with Tricuspid Regurgitation Due to a Structural Defect of the Septal Leaflet After Surgical Leaflet Repair
Left Atrial Appendage Closure
Front Matter
Percutaneous Left Atrial Appendage Closure: Rationale, Patient Selection, and Preoperative Evaluation
Preprocedural Imaging for Left Atrial Appendage Occlusion
Left Atrial Appendage Closure: Techniques and Devices
Left Atrial Appendage Closure
Difficult Cases and Complications from the Catheterization Laboratory: Case 2
Patent Foramen Ovale, Interatrial Defect Closure and Other Interventions
Front Matter
Indications, Imaging, and Patient Selection for Patent Foramen Ovale and Interatrial Defects
Patent Foramen Ovale Closure—From Anatomy to Device Selection and Step-by-Step Procedure
Interatrial Defects: Techniques and Devices
Difficult Cases and Complications from the Catheterization Laboratory—A Case of Nitinol Intolerance
Difficult Cases and Complications from Catheterization Laboratory: Case 1 Device Embolization After PFO Closure
Paravalvular Regurgitation: Techniques, Access Selection, and Devices
Editors and Affiliations
Interv. Cardiol. Unit Cardio Center, IRCCS Humanitas Research Hospital, Rozzano, Italy
Bernhard Reimers, Antonio Mangieri
Structural Heart Interventions, Montefiore Medical Center, New York, USA
Azeem Latib
Heart & Vascular Institute, Carle Illinois College of Medicine, Univ. of Illinois at Urbana-Champaign, Urbana, USA
Issam Moussa
Intervent. Cardiol. Unit Cardio Center, IRCCS Humanitas Research Hospital, Rozzano, Italy
Damiano Regazzoli
Azienda Ospedaliero-Universitaria Verona, Verona, Italy
Andrea Pacchioni
About the editors
Bernhard Reimers is Director of the Clinical and Invasive Cardiology at Humanitas Research Hospital, Milan, Italy. Born in Germany and living in Italy since 1984, he earned his medical degree from the University of Padua in 1990. Followed by a period as Junior House Officer in internal medicine in UK and by a cardiology residency at the University Hospital of Padua (1991-1995). After a fellowship at the Thoraxcenter in Rotterdam he trained as interventional cardiologist in Milan under dr. Antonio Colombo (1995-1997). Subsequently he developed a highly successful cardiovascular program at Mirano Hospital, Venice, Italy. Since 2015 at Humanitas, he leads a high-volume program in coronary and structural heart interventions. He is a global expert in carotid angioplasty. Dr. Reimers has contributed extensively to research on complex coronary interventions and TAVR, publishing numerous articles and performing live procedures at international conferences. He also organizes major cardiology events such as TOBI (Total Occlusions and Bifurcations) and MVSIC (Milan Valve Structural and Interventions Course). He trained numerous assistants and fellows from Italy and from all over the world. Most of these, subsequently and to his pride, made a brilliant career in interventional cardiology.
Azeem Latib is System Director of Interventional Cardiology and Structural Heart Interventions at Montefiore Health System and Professor of Medicine at Albert Einstein College of Medicine, New York. An expert in interventional cardiology, he specializes in complex coronary procedures and transcatheter valve interventions (TAVR, TMVI, TTVI, and others). He earned his medical degree in 1995 from the University of Witwatersrand, South Africa, and completed advanced training in South Africa and Italy. Since 2019, he has led Montefiore’s interventional cardiology unit. His research focuses on structural heart devices, drug-coated balloons, and stents. Dr. Latib has authored over 900 peer-reviewed publications. He serves on editorial boards, international conference faculties, and is a member of the ACC and ESC. He is Global PI of multiple international and FDA-approved trials and has helped pioneer several novel interventional devices.
Antonio Mangieri, MD, is an interventional cardiologist at Humanitas Research Hospital IRCCS in Rozzano, Milan. He earned his medical degree and completed cardiology residency at Vita-Salute San Raffaele University, where he also obtained a Master’s in Interventional Cardiology. His clinical and research interests include complex percutaneous coronary interventions, structural heart disease, and transcatheter valve therapies, with expertise in TAVI, mitral and tricuspid interventions, and intracoronary imaging. Dr. Mangieri has authored over 250 peer-reviewed publications, including work on conduction disturbances, valve-in-valve procedures, and imaging in complex PCI. He participates in multicenter trials and speaks regularly at international congresses such as EuroPCR and TCT.
Issam D. Moussa is Professor and Head of the Department of Cardiovascular Medicine & Surgery at Carle Illinois College of Medicine, University of Illinois, Urbana-Champaign. He earned his medical degree from the University of Damascus and completed postgraduate studies at UC Irvine, Centro Cuore Columbus, and Lenox Hill Heart & Vascular Institute. A specialist in complex coronary and structural interventions, Dr. Moussa is a prolific researcher with numerous peer-reviewed publications. He serves on key committees of the ACC, AHA, and SCAI, including Chair of the ACC CathPCI Registry Steering Committee.
Damiano Regazzoli is an interventional cardiologist at Humanitas Research Hospital. He graduated from the University of Brescia and completed training at Vita-Salute San Raffaele University. He joined Humanitas in 2018 and is active in national and international societies (GISE, ESC, EAPCI). His research focuses on bioresorbable scaffolds, TAVI, mitral/tricuspid interventions, and mechanical circulatory support.
Andrea Pacchioni is an interventional cardiologist at Mirano Hospital, Italy. He graduated from the University of Milan and trained at the University of Verona. Since 2010, he has led interventional activities at Mirano and co-founded the CTO Club Triveneto. He is faculty at major meetings (TOBI, TCT, AIM Radial) and focuses on chronic total occlusions, transradial access, and high-risk interventions.
Bibliographic Information
- Hardcover ISBN978-3-032-04994-0Published: 20 February 2026
- Softcover ISBN978-3-032-04997-1Due: 06 March 2027
- Edition Number2
- Number of PagesXV, 527
- Number of Illustrations49 b/w illustrations, 237 illustrations in colour
- Topics Cardiology, Internal Medicine, Surgery
Keywords
- Aortic stenosis
- Interatrial defects
- Left atrial appendage closure
- Mitral regurgitation
- Patent foramen ovale closure
- Structural heart intervention
- TAVI
- tricuspid regurgitation
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