Asthma and Severe Asthma, 1st Edition / Author: Claudio Sorino

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Reflects a nuanced, evidence-based approach to diagnosis, treatment options, and follow-up criteria, including a comprehensive section on difficult-to-treat and severe asthma

Offers a case-based, problem-solving structure in every chapter: real patient presentation, step-by-step diagnostic workup, multidisciplinary expert discussion, clinical course, follow-up, and outcomes

Offers practical advice on evolving guidelines, including the rapid expansion of biologic options (omalizumab, benralizumab, mepolizumab, dupilumab, tezepelumab) and the shift toward T2/non-T2 endotyping

 

 

Descripción

 

ISBN Number9780443119811
Main AuthorClaudio Sorino
Copyright Year2028
Edition Number1
FormatBook
Trim6 x 9 mm
ImprintElsevier
Page Count240
Publication Date1 Mar 2027
Stock StatusPre-order now and your purchase will be shipped following the release on 3/1/27

 

 

Part of Dr. Claudio Sorino’s popular Clinical Cases and Real-World Discussions series, Asthma and Severe Asthma brings you up to date with the latest advances in this fast-changing field. Using a unique, case-based approach, a wide variety of cases are presented along with perspectives from a multidisciplinary team of experts who discuss therapeutic choices and rationales. This real-world approach allows the reader to become a virtual attending physician, simulating a realistic clinical reasoning process on the diagnosis, treatment, and follow-up of patients with asthma. Cases cover the full clinical spectrum, from common comorbid scenarios such as allergic rhinitis, GERD, OSA, or obesity, through rare and or more extreme presentations such as asthma in a tracheostomized patient in a minimally conscious state or EGPA with mononeuritis multiplex.

Key Features

  • Reflects a nuanced, evidence-based approach to diagnosis, treatment options, and follow-up criteria, including a comprehensive section on difficult-to-treat and severe asthma

 

  • Offers a case-based, problem-solving structure in every chapter: real patient presentation, step-by-step diagnostic workup, multidisciplinary expert discussion, clinical course, follow-up, and outcomes

 

  • Offers practical advice on evolving guidelines, including the rapid expansion of biologic options (omalizumab, benralizumab, mepolizumab, dupilumab, tezepelumab) and the shift toward T2/non-T2 endotyping

 

  • Provides multidisciplinary perspectives in every case, with input from pulmonology, allergy/immunology, rheumatology, cardiology, geriatrics, otolaryngology, and other specialties, reflecting how complex asthma is actually managed

 

  • Features dozens of illustrations throughout, including chest CT scans, spirometry tracings, bronchoscopy images, histopathology specimens, clinical photographs, and diagnostic algorithm infographics

 

  • Uses recurring Discussion, Focus On, and Learning Points boxes in every chapter that make content easy to navigate and ideal for reviewing as needed

 

  • concise point-of-care reference for today’s pulmonologists, as well as anyone who is interested in an interactive approach to everyday clinical problems related to asthma and severe asthma

 

  • An eBook version is included with purchase. The eBook allows you to access all of the text, figures, and references, with the ability to search, make notes and highlights, and have content read aloud. Additional digital ancillary content may publish after the publication date

 

TABLE OF CONTENTS

Section 1: Asthma and Comorbid Conditions
1. Allergic Rhinitis and Asthma
2. Asthma and Obstructive Sleep Apnea
3. Poorly Controlled Asthma and Gastroesophageal Reflux Disease
4. Atopic Dermatitis, Asthma, and Allergic Bronchopulmonary Aspergillosis
5. Asthma and Obesity
6. Asthma and Interstitial Lung Disease

Section 2: Particular Phenotypes of Asthma
7. Asthma and Coronary Artery Disease
8. Childhood Asthma
9. Late-onset Eosinophilic Asthma
10. Asthma and Pregnancy
11. Overlap COPD and Asthma with Fungal Sensitization
12. Asthma in Aspirin-exacerbated Respiratory Disease
13. Asthma and Alpha-1 Antitrypsin Deficiency

Section 3: Challenging Diagnosis of Asthma
14. Long-Standing Asthma and Persistent Airflow Limitation
15. Cough-Variant Asthma: Clinical Challenges and Differential Diagnosis
16. Exercise-Induced Bronchoconstriction and Exercise-Induced Laryngeal Obstruction
17. Sensitiser-induced Occupational Asthma and Rhinitis
18. Wheezing with Normal Spirometry: Diagnostic Challenges and Risk of Near-Fatal Exacerbations
19. Asthma in the Elderly
20. Severe Asthma and Tracheostomy

Section 4: Difficult to Treat and Severe Asthma
21. Severe Asthma with Perennial Aeroallergen Sensitization
22. Severe Allergic Eosinophilic Asthma and Bronchiectasis
23. Severe Non-allergic Eosinophilic Asthma
24. Severe Early-Onset Allergic Asthma and Chronic Rhinosinusitis With Nasal Polyposis: Guiding Biologic Therapy
25. Severe Asthma and Eosinophilic Granulomatosis with Polyangiitis Requiring Biological Therapy
26. Targeting Thymic Stromal Lipoprotein in Severe T2-low Asthma
27. Dual Biologic Therapy in Severe Asthma and Chronic Rhinosinusitis with Nasal Polyposis

Author Information

Claudio Sorino,Professor of Medicine and Associate Medical Director, Respiratory Pathophysiology Unit, Department of Pulmonary and Critical Care Medicine, Sant’Anna Hospital, Como, Italy

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